Heterogeneous catalyst for the hydrogenation of aromatics.
Silica supported ruthenium nanoparticles stabilized with a family of phosphine ligands represent a new class of robust catalysts with high performance in mild conditions for the full hydrogenation of aromatic compounds such as phthalates, acetophenone, etc.
High yielding reduction of CO2 to methanol.
A continuous flow process realizing the preparation of methanol from carbon dioxide with close to quantitative yields in one sole pass through the reactor has been developed. Methanol can then further be processed to dimethylether (DME) and hydrocarbons.
Chiral monomer obtained from furfural (biomass) for applications in polymers.
A process allowing for the obtention of a chiral 1,2-diol derived from furfural has been developed. The process is highly selective and high yielding. An industrial (SME or large company) or academic partner is sought for the joint development of polymers based on this monomer (polyurethanes, polyesters or polycarbonates). Technology is available for licensing and/or joint development.
SCIPIO: a comprehensive software interface for computational chemists.
SCIPIO is a software that allows to handle, store and manipulate output files from computational chemistry experiments. SCIPIO is a general data extractor and manager that is here presented as a Computational Chemistry Results Repository, which is a sort of tailored electronic notebook allowing for substructure searches and for the generation of “ready to publish” reports.
Cinchona alkaloid derivatives as organocatalysts.
ICIQ is searching for licensees, product distributor and/or manufacturer for a series of 8 cinchona alkaloid derivatives, bearing a primary amine functionality and useful as organocatalysts of a broad range of reactions. These compounds are prepared in a divergent synthesis, using readily available quinine and quinidine as starting materials.
Homogeneous water oxidation catalyst for use in fuel cells.
A stable, inorganic homogeneous catalyst for water oxidation to molecular oxygen has been developed. This cobalt-based catalyst is the most efficient homogeneous one discovered to date and can be used to electrolyze water into hydrogen and oxygen at neutral pH, which enables to store chemically sunlight energy. Technology is available for out-licensing and joint development.
Shelf-stable trifluoromethyl copper complex.
ICIQ is searching for licensees, product distributor and/or manufacturer for a trifluoromethyl copper coordination complex useful in trifluoromethylation of aromatics and other electrophiles. The offered compound has the benefit of being air-stable in the solid state and is prepared from readily available and stable starting materials.
Hypervalent iodine reagents for amination reactions.
New reagents based on hypervalent iodine compounds that readily react with a wide substrate family to form the corresponding aminated products. Particularly, alkenes readily react to give the corresponding 1,2-diamine and enolizable ketones lead to the formation of the corresponding a-aminoketo derivative. Enantioselective 1,2-diamination of some alkenes was also developped.
Trifluoromethylcopper reagents from fluoroform.
A new process for the preparation of a trifluoromethylating agent from fluoroform was developped. This process advantageoulsy takes place at room temperature and forms a stable trifluoromethylcopper reagent useful in trifluoromethylation reactions. A partner for process optimization and adaptation to specific needs is sought.
cLab: a web portal to access, use and manage computational resources.
The Computational Laboratory Web Manager (cLab) is a web portal that permits the access and the management of a computational laboratory, which is a high performance hypercomputation center based on heterogeneous clusters of computers and used by multiple users simultaneously for the execution of computational jobs.
Purification of fullerenes by selective encapsulation mediated solid-liquid extraction.
A concave compound self assembles thanks to reversible and controlable hydrogen bonding to form a dynamic capsule able to selectively extract fullerene derivatives of given size and shape.
Universidad de Valladolid
Recyclable polymeric tin reagents supported on vinylic polynorbornenes.
A new type of stannylated polymers based on the robust vinylic polynorbonene backbone are suitable reagents in the Stille coupling or other organotin‐based reactions. The tin polymers are recyclable and can be immobilized and used in a batch procedure. The products are obtained following a very simple workup and have very low tin contamination.
Vinylic polynorbornenes as non‐reactive supports.
Functionalized vinylic polynorbornenes can be obtained by copolymerization of norbornene and haloakyl substituted norbornenes. Substitution of the halogen by other functional groups of interest is possible. Thus, these new polymers are good precursors to support catalysts or reagents on the vinylic polynorbornene skeleton, which is thermally stable, and robust under most reaction conditions.
Enantioselective addition of organozincs to aryltrifluoromethyl ketones.
Chiral alcohols bearing a CF3 substituent are the head of series of molècules actively investigated against Tipe II diabetes and obesity. These can be prepared enantioselectively in high enantiomeric excess by a catalytic procedure that allows the addition of ZnMe2 and ZnEt2 to different Ar‐C(O)‐ CF3 substrates in a single step. Our procedure can replace advantageously the actual multistep racemic procedure. Moreover, it allows for the synthesis of unreported chiral alcohols ArEt(CF3)C‐OH, which are also covered in this patent.