When we first heard of the Bürgenstock conference it was described as a guarded meeting in a remote location, undisturbed by modern diversions, with mysterious customs and a secret handshake. All of these rumors turned out to be completely true. We arrived at an undisclosed location and three young men, who knew our names upon sight, greeted us and gave us an agenda in which we discovered the identity of the speakers, moderators and other participants. We then had a few moments to bask in their glory before being treated to a delicious dose of chemistry. During the banquet, before the first lecture, this year’s president, Prof. Ilan Marek, gave the opening address from a balcony reserved only for these meetings, rumors hold that it stands vacant all year in anticipation. He mentioned several of the traditions of the meeting, which we are not allowed to share of course, and described the joy of putting together this year’s exciting program with the help of an exceptional organizing committee that included Prof. Cristina Nevado, Prof. Christian Bochet, Dr Fabrice Gallou and Dr Alain De Mesmaeker. He also introduced this year’s guest of honor, Prof. Yitzhak Apeloig, and wished the best luck to the current Vice President and future President, Prof. Véronique Gouverneur, not only for preparing the 54th Bürgenstock Conference, but also with her duty this year, maintaining the good weather for the whole week. Although the official title of the conference is the EUCHEM conference on stereochemistry, the topics covered span a broad range of cutting edge chemical transformations and insights, which can appeal to anyone working in chemistry and its interfaces with other disciplines. We will briefly describe each of the talks following one of our favorite citable quotes from these inspiring speakers.