The paper by Ruben Martin and Cayetana Zárate describes a Ni/Cu-catalyzed silylation of unactivated C–O electrophiles derived from phenols or benzyl alcohols. This transformation is characterized by its wide scope and mild conditions, providing a direct access to synthetically versatile silylated compounds. The protocol allows for the coupling of C(sp2)?O and even C(sp3)–O bonds with similar efficiency.
A Mild Ni/Cu-Catalyzed Silylation via C–O Cleavage
Cayetana Zarate and Ruben Martin
J. Am. Chem. Soc, 2014, 136 (6), pp 2236–2239
This paper is one of most read articles of JACS in February.