A base-mediated protocol that allows for the site-selective sp2 C–H silylation of azines is described. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a diverse set of azines, even in the context of late-stage functionalization, while exhibiting orthogonal reactivity with classical silylation reactions.
A Mild and Direct Site-Selective sp2 C–H Silylation of (Poly)Azines
J. Am. Chem. Soc. 2019, 141 (1), 127-132, DOI: 10.1021/jacs.8b12063.