The original Stille protocols for cross-couplings are difficult to recognize in the newer nickel-catalyzed reactions of monoorganotin compounds with secondary alkyl halides (see scheme). This new coupling scheme avoids the formation of toxic byproducts.
![Couplings with monoorganotin compounds: A “radical” twist from the original Stille reaction](https://www.iciq.org/wp-content/uploads/2014/03/Couplings-with-monoorganotin_eng_noticies_articles_2005_11.gif)