Palladium and nickel are used in conjunction with titanocene(III) complexes to perform selective allylations of carbonyl compounds and alkenes, respectively. Pd/Ti-catalyzed allylation of ketones proceeds diastereoselectively under mild conditions, whereas Ni/Ti-promoted cyclizations provide polyalkyl-substituted carbo- and heterocycles with excellent control over regio- and stereoselectivity.
Divergent titanium-mediated allylations with modulation by nickel or palladium
Angew. Chem. Int. Ed. 2008, 47, 7515-7519.