Abstract

The involvement of Metal-Organic Frameworks (MOFs) in biomedical applications is currently one of the hot topics in the emerging field of hybrid porous solids. In particular, nanometric iron carboxylate MOFs (nanoMOFs) have recently attracted a great deal of attention owing to their large porosity and versatile composition, enabling to entrap remarkable loadings of a wide variety of challenging molecules, including drugs and toxins. However, for the practical use of MOF nanocarriers, it is necessary to investigate their safety, biodistribution and efficiency.

Further, the therapeutic misadventures, illicit drug ingestion or attempted suicide by using of drug overdoses is a major worldwide public health problem. Unfortunately, current treatments are accused of being ineffective and even of causing unnecessary complications. In this context, MOFs has also recently demonstrated to be promising safe and efficient oral detoxification agents. MOFs can not only acts as contaminant adsorbents in the body, but also in polluted water, selectively removing emerging organic contaminants by adsorption and photocatalytic degradation, improving the performance of the current materials.

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According to the last information received from ICIQ’s safety department about the measures to prevent and contain COVID-19 at ICIQ, a total of 50 people is now the maximum capacity allowed in the Auditorium, so the Thesis Defense will be finally held in the Auditorium as well as through ZOOM platform too.

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