The aim of SYNFACTS is to inform you, on a monthly basis and in a concise manner, of the most significant recent developments and future trends in synthetic chemistry in order to stimulate your own research and the development of exciting new ideas.
We are therefore delighted that the latest paper by Prof. Kilian Muñiz and Dr. Claudio Martínez has been selected by the editorial board of Synfacts.
The paper deals with the Pd(II)/Pd(IV) – catalysed diamination of internal alkenes and the corresponding diastereoselective synthesis of diamines. The authors present a good substrate scope with moderate to excellent yields. The resulting diamination products can be converted directly into a known ligand motif.
Palladium-catalyzed vicinal difunctionalization of internal alkenes: Diastereoselective synthesis of diamines
C. Martínez, K. Muñiz
Angew. Chem. Int. Ed. 2012, 51, 7031-7034